At Renue Wellness in New Hyde Park, we specialize in helping patients find rapid relief from treatment-resistant depression through Spravato® (esketamine) — an FDA-approved nasal spray that works differently than traditional antidepressants.
Our team provides a safe, comfortable, and medically supervised environment for patients throughout Long Island, Nassau County, Queens, and Suffolk County seeking proven, evidence-based depression treatment.
Spravato® is the brand name for esketamine, a prescription nasal spray developed by Janssen Pharmaceuticals and approved by the U.S. Food and Drug Administration (FDA) in 2019 for adults with treatment-resistant depression (TRD) and major depressive disorder (MDD) with suicidal thoughts or actions.
Unlike standard antidepressants, which can take weeks to work, Spravato® acts on the glutamate system — a key neurotransmitter involved in mood regulation. This unique mechanism helps restore healthy brain activity and can lead to noticeable symptom relief within hours or days.
When administered under medical supervision, Spravato® enters the bloodstream through the nasal passages and stimulates NMDA (N-methyl-D-aspartate) receptors in the brain.
This activation encourages neural growth and connectivity, helping reverse the patterns of negative thought and emotional stagnation commonly seen in depression.
Patients typically begin to experience improvement after a few sessions, with full treatment plans tailored to individual needs.
Clinical Fact: In trials, patients using Spravato® with an oral antidepressant showed significant improvement in depressive symptoms compared to placebo within four weeks.
Your Spravato® journey begins with an evaluation by one of our licensed providers. We review your medical history, current symptoms, and previous treatments to determine candidacy.
Spravato® is administered as a nasal spray in our New Hyde Park clinic under medical supervision. You’ll be monitored for approximately 2 hours after each session for comfort and safety.
Typical Spravato® treatment schedules involve:
Each treatment plan is customized to support long-term mood stability and wellness.
Our clinic is conveniently located at 1 Hollow Ln #201A, North New Hyde Park, NY 11042, just off Marcus Avenue near major highways.
Nearby Landmarks for Easy Access:
You may be a candidate for Spravato® if you:
Spravato® may not be appropriate for individuals with certain medical conditions — our providers conduct a thorough assessment to ensure suitability and safety.
Yes — Spravato® is covered by many major insurance providers, including commercial plans and Medicare.
At Renue Wellness, our team assists each patient in verifying benefits and determining coverage before beginning treatment. Because Spravato® is an FDA-approved therapy for depression, it often qualifies for medical insurance coverage, unlike IV ketamine therapy which is typically self-pay.
We also welcome patients with out-of-network benefits and offer financing through Care Credit and Advanced Care.
Learn more about our financing options.
As part of the SPRAVATO® treatment regimen, the FDA-required Risk Evaluation and Mitigation Strategy (REMS) is implemented to ensure patient safety and optimal outcomes. During your initial relief phase, you may have the opportunity to implement positive life changes to manage depression symptoms as they return. While ongoing maintenance appointments are often necessary every 4-6 weeks after the initial treatment, our priority is to provide comprehensive support, allowing you to sustain the positive results achieved through SPRAVATO® treatment.
Yes — Spravato® (esketamine) is FDA-approved and has undergone extensive clinical trials demonstrating both its safety and effectiveness for treatment-resistant depression (TRD). At Renue Wellness, every Spravato® treatment is medically supervised in a controlled clinical setting to ensure your comfort and well-being. Patients are closely monitored before, during, and after each session by licensed healthcare professionals.
Yes, in most cases. Because Spravato® is FDA-approved, it is covered by many major insurance providers, including commercial plans and Medicare.
At Renue Wellness, our administrative team will verify your insurance benefits, help with prior authorization, and guide you through any copay assistance programs offered by Janssen CarePath (Spravato’s manufacturer). This ensures patients can access treatment affordably and without unnecessary delays.
Yes — if you live on Long Island, in Nassau County, Queens, or Suffolk County, you can receive Spravato® treatment right here at Renue Wellness in New Hyde Park, NY.
Our clinic is conveniently located near Northwell Health, Marcus Avenue, and major highways, making it easy for patients throughout Long Island and the surrounding areas to access care.
Most patients tolerate Spravato® very well. However, some may experience temporary side effects such as:
These effects are short-lived and are carefully monitored by our medical staff during your in-clinic session. Most patients feel completely back to normal within a few hours after treatment.
Spravato® often provides rapid relief — many patients notice an improvement in mood and energy within 24 to 48 hours after the first few treatments. This is much faster than traditional antidepressants, which may take weeks to become effective.
For lasting results, most patients continue with a full 6- to 8-week treatment protocol, followed by maintenance sessions as needed.
Each Spravato® session takes about 2 hours in total. This includes time for nasal administration, resting and observation, and post-treatment recovery.
Because of potential mild drowsiness, we recommend arranging transportation after each session — you should not drive yourself home.
You may be a good candidate for Spravato® treatment if you:
Spravato® is not recommended for individuals with certain conditions (such as aneurysmal vascular disease or a history of hypersensitivity to esketamine).
At Renue Wellness, your provider will evaluate your full medical history before approving treatment.
Clinical studies show that up to 70% of patients with treatment-resistant depression experience significant improvement after completing a Spravato® protocol. In combination with oral antidepressants, Spravato® has also been shown to reduce suicidal ideation and improve daily functioning.
At Renue Wellness, our patients often report feeling emotional clarity, increased motivation, and an improved sense of well-being after several sessions.
No — patients should not drive, operate machinery, or engage in any potentially hazardous activities until the day after their Spravato® session. Because the medication can cause temporary drowsiness or dissociation, you’ll need to arrange transportation home following each appointment.
Our team will monitor you for approximately 2 hours after administration to ensure you feel safe and stable before leaving the clinic.
Spravato® is only available through certified treatment centers like Renue Wellness, as part of the Spravato® REMS (Risk Evaluation and Mitigation Strategy) program. This means it can only be administered in a medical office under direct supervision — it is not available for at-home use.
At our New Hyde Park clinic, patients receive Spravato® in comfortable, private treatment suites with one-on-one medical monitoring throughout each session.
If you’re struggling with depression that hasn’t improved with medication or therapy, Spravato® may be the breakthrough you’ve been waiting for.
Schedule your consultation at Renue Wellness in New Hyde Park, Long Island, and take the first step toward lasting mental wellness today.
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